Related Experiment Video
Updated: Jul 6, 2026

Preparation of 6-aminocyclohepta-2,4-dien-1-one Derivatives via Tricarbonyl(tropone)iron
Published on: August 12, 2019
A [4Fe-4S] cluster dimer bridged by bis(2,2':6',2''-terpyridine-4'-thiolato)iron(II)
Erwin P L van der Geer1, Gerard van Koten, Robertus J M Klein Gebbink
1Chemical Biology & Organic Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Abstract:
The use of 2,2':6',2''-terpyridine-4'-thiol (tpySH) was explored as a bridging ligand for the formation of stable assemblies containing both [4Fe-4S] clusters and single metal ions. Reaction of tpySH (2 equiv) with (NH4)2Fe(SO4)(2).6H2O generated the homoleptic complex [Fe(tpySH)2](2+), which was isolated as its PF6(-) salt. The compound could be fully deprotonated to yield neutral [Fe(tpyS)2], and the absorption spectrum is highly dependent on the protonation state. Reaction of [Fe(tpySH)2](PF6)2 with the new 3:1 site-differentiated cluster (n-Bu4N)2[Fe4S4(TriS)(SEt)] yielded the first metal-bridged [4Fe-4S] cluster dimer, (n-Bu4N)2[{Fe4S4(TriS)(mu-Stpy)}2Fe]. Electrochemical studies indicate that the [4Fe-4S] clusters in the dimer act as independent redox units, while UV-vis spectroscopy provides strong evidence for a thioquinonoid electron distribution in the bridging tpyS(-) ligand. TpySH thus acts as a directional bridging ligand between [4Fe-4S] clusters and single metal ions, thereby opening the way to the synthesis of larger, more complex assemblies.
More Related Videos
12:30Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
Published on: April 9, 2018
12:43The Synthesis of [Sn10(Si(SiMe3)3)4]2- Using a Metastable Sn(I) Halide Solution Synthesized via a Co-condensation Technique
Published on: November 28, 2016
Related Concept Videos
Preparation and Reactions of Sulfides
Structure of Benzene: Kekulé Model
He proposed that benzene has a cyclic structure of six carbon atoms attached to one hydrogen atom each, with three alternating pi bonds.
Valence Bond Theory
Hybridization of Atomic Orbitals II
Structure and Nomenclature of Thiols and Sulfides
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...