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Divergence and Stokes' Theorems01:06

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The divergence and Stokes' theorems are a variation of Green's theorem in a higher dimension. They are also a generalization of the fundamental theorem of calculus. The divergence theorem and Stokes' theorem are in a way similar to each other; The divergence theorem relates to the dot product of a vector, while Stokes' theorem relates to the curl of a vector. Many applications in physics and engineering make use of the divergence and Stokes' theorems, enabling us to write numerous physical laws...
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Transmission lines are essential components of electrical power systems. They are characterized by the distributed nature of resistance (R), inductance (L), and capacitance (C) per unit length. To analyze these lines, differential equations are employed to model the variations in voltage and current along the line.
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Related Experiment Video

Updated: Jul 6, 2026

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180&#176; Curved Artery Test Section
11:00

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

A differential fluctuation theorem.

Paul Maragakis1, Martin Spichty, Martin Karplus

  • 1Department of Chemistry & Chemical Biology, Harvard University, Cambridge, MA 02138, USA. paul.maragakis@deshaw.com

The Journal of Physical Chemistry. B
|March 12, 2008
PubMed
Summary
This summary is machine-generated.

We developed a new nonequilibrium thermodynamics identity to calculate free energy differences between states. This differential fluctuation theorem simplifies analysis of molecular dynamics simulations and laboratory experiments.

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From Fast Fluorescence Imaging to Molecular Diffusion Law on Live Cell Membranes in a Commercial Microscope
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Published on: October 9, 2014

Related Experiment Videos

Last Updated: Jul 6, 2026

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180&#176; Curved Artery Test Section
11:00

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

From Fast Fluorescence Imaging to Molecular Diffusion Law on Live Cell Membranes in a Commercial Microscope
15:10

From Fast Fluorescence Imaging to Molecular Diffusion Law on Live Cell Membranes in a Commercial Microscope

Published on: October 9, 2014

Area of Science:

  • Thermodynamics
  • Statistical Mechanics
  • Physical Chemistry

Background:

  • Non-equilibrium thermodynamics studies systems driven far from equilibrium.
  • Estimating free energy differences is crucial for understanding molecular behavior.
  • Existing methods can be computationally intensive or limited in scope.

Purpose of the Study:

  • To derive a novel nonequilibrium thermodynamics identity, the differential fluctuation theorem.
  • To establish a method for estimating free energy differences between states.
  • To demonstrate the theorem's applicability to molecular systems.

Main Methods:

  • Derivation of the differential fluctuation theorem from Crooks' fluctuation theorem.
  • Application of the theorem to analyze joint probabilities of work and generalized coordinates.
  • Utilizing molecular dynamics simulations for validation.

Main Results:

  • The differential fluctuation theorem connects forward and reverse probabilities of work and state coordinates.
  • The theorem provides a direct method for estimating free energy differences.
  • Successful estimation of free energy differences for alanine dipeptide conformers.

Conclusions:

  • The differential fluctuation theorem offers a powerful tool for nonequilibrium thermodynamics.
  • This approach simplifies free energy calculations in molecular simulations.
  • Potential for broad application in analyzing experimental data.