Related Experiment Video

Updated: Jul 6, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

RAGE in diabetic nephropathy

Hiroshi Yamamoto1, Takuo Watanabe, Yasuhiko Yamamoto

  • 1Department of Biochemistry and Molecular Vascular Biology, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa 920-8640, Japan. yamamoto@med.kanazawa-u.ac.jp

Current Molecular Medicine
|March 12, 2008
PubMed
Summary

Advanced glycation endproducts (AGE) and their receptor (RAGE) drive diabetic nephropathy. Targeting AGE and RAGE pathways offers a promising therapeutic strategy for preventing kidney disease in diabetics.

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