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Identification of the novel HLA-A*240215 allele by haplotype-specific sequencing

F Emmerich1, C Schönemann, S Hartmann

  • 1Center for Tumor Medicine, Institute for Transfusion Medicine, Charité University Medicine, Berlin, Germany. florian.emmerich@charite.de

Tissue Antigens
|March 12, 2008
PubMed

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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