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Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
Published on: October 1, 2016
"Click-fluors": modular fluorescent saccharide sensors based on a 1,2,3-triazole ring
David K Scrafton1, James E Taylor, Mary F Mahon
1Department of Chemistry, The University of Bath, Claverton Down, Bath, BA2 7AY, UK.
Abstract:
A carbohydrate sensing "click-fluor" is reported which displays a nontypical binding preference with sample saccharides. That a fluorescent sensor is generated as a result of triazole formation (click reaction), rather than simply bringing the sensor and reporter units together via a triazole linkage, and the potential applicability of the wide range of easily accessible acetylene units means a simple strategy for the development of modular fluorescent sensor arrays for rapid screening of target saccharides will be available.
