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Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization

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Microarray: an approach for current drug targets.

Virendra S Gomase¹, Somnath Tagore, Karbhari V Kale

¹Department of Bioinformatics, Dr. D.Y. Patil Institute for Biotechnology and Bioinformatics, Padmashree Dr. D.Y. Patil University, Plot No-50, Sector-15, CBD Belapur, Navi Mumbai, 400614, India. virusgene1@yahoo.co.in

Current Drug Metabolism

|March 14, 2008

Summary

This summary is machine-generated.

Microarray technology enables early assessment of drug targets and pharmacogenomics. Advances in genomics and microarray analysis reveal novel targets for drug design and research into common diseases.

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Area of Science:

Genomics
Molecular Biology
Pharmacogenomics

Background:

Microarrays are versatile tools in clinical and biological research.
They facilitate the study of gene expression and identify potential drug targets.

Purpose of the Study:

To review microarray technologies and their applications.
To discuss current drug targets relevant to common diseases.

Main Methods:

Comparative gene expression analysis using microarrays.
Review of recent advances in genomics and drug target identification.

Main Results:

Identification of novel drug candidates and intervention targets.
Applications in pharmacogenomics, toxicogenomics, and single nucleotide polymorphism (SNP) analysis.

Conclusions:

Microarray analysis, coupled with genomic data, offers new avenues for drug discovery.
This technology is crucial for understanding common diseases and future therapeutic strategies.