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A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice
Published on: May 10, 2013
The auxiliary table for GFR estimation according to the MDRD formula
Milena Stollová1, Otto Schuck, Ivana Smrcková
1Institute for Clinical and Experimental Medicine, Prague, Czech Republic. milena.stollova@ikem.cz
Journal of Renal Care
|March 14, 2008
Summary
Glomerular filtration rate (GFR) assesses kidney function. This study provides a table for calculating estimated GFR using the MDRD formula where computer programs are unavailable, simplifying renal function assessment.
Area of Science:
- Nephrology
- Renal Physiology
Background:
- Glomerular filtration rate (GFR) is the primary indicator of kidney function.
- Renal inulin clearance (Cin) is the gold standard for GFR assessment but is impractical for routine use.
- Commonly used methods include the Cockcroft-Gault (CG) formula and the MDRD equation.
Purpose of the Study:
- To provide a practical tool for estimating GFR in resource-limited settings.
- To facilitate routine renal function assessment without computer access.
Main Methods:
- The study focuses on the Modification of Diet in Renal Disease (MDRD) prediction equation.
- A table is presented for simplified MDRD-based GFR calculation.
Main Results:
- The provided table allows for manual calculation of estimated GFR.
- This method bypasses the need for computer programs.
Conclusions:
- The table serves as a valuable resource for estimating GFR in areas lacking computational tools.
- It simplifies the assessment of renal function for healthcare providers globally.
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