Related Experiment Video
Updated: Jul 6, 2026
Novel Surgical Rodent Model for Studying Neuroma Pain Treatment Options using Targeted Muscle Reinnervation Through the Saphenous Nerve
Published on: November 14, 2025
Sequelae following sural nerve biopsy in type 1 diabetic subjects
L B Dahlin1, F Lithner, L-E Bresäter
1Department of Clinical Sciences, Hand Surgery, University Hospital Malmö, Malmö, Sweden. Lars.Dahlin@med.lu.se
Objectives:
To detect post-operative sequelae of sural nerve biopsy.
Materials And Methods:
A questionnaire mailed to type 1 diabetic patients (n = 24; male/female 23/1; reply n = 23) 2 years after biopsy.
Results:
Type 1 diabetic patients (age 56 [11]; median [interquartile range]) had a long duration of diabetes (DM; 20 [19] years) and all had neuropathy. Three out of 24 patients developed infection (two superficial and one deep) and one had a post-operative bleeding. Less frequent pain among the patients were reported from one centre. About one-third or more of the patients still complained of pain, mostly mild, in the biopsy area and paraesthesia in the foot 2 years after surgery. More than two-thirds of the patients were reluctant for further biopsy; a crucial information in drug trial planning.
Conclusions:
Sequelae of a sural nerve biopsy occur in type 1 DM. The risk for wound infections should be considered.
Related Concept Videos
01:22Diabetic Neuropathy
01:19Type I Diabetes III: Clinical Manifestations
01:26Type I Diabetes II: Pathophysiology
01:22Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...