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Acute otitis media in the first two months of life: characteristics and diagnostic difficulties
Y Berkun1, R Nir-Paz, A Ben Ami
1Department of Pediatrics, Bikur Cholim Hospital, Jerusalem, Israel. berkun@post.tau.ac.il
Insights
Diagnosing acute otitis media (AOM) in infants under two months is challenging. Bacterial AOM often lacks clear predictors, suggesting empirical antibiotics are needed, and paediatrician diagnostic accuracy requires improvement.
Area of Science:
- Pediatrics
- Infectious Diseases
- Otolaryngology
Background:
- Acute otitis media (AOM) is a common childhood infection.
- Diagnosis and management in neonates and young infants present unique challenges.
- Accurate identification of bacterial pathogens is crucial for effective treatment.
Purpose of the Study:
- To characterize clinical and laboratory findings of AOM in infants < 2 months.
- To identify predictors of bacterial AOM in this age group.
- To evaluate the diagnostic accuracy of paediatricians for AOM in young infants.
Main Methods:
- Retrospective cohort study of 277 hospitalized infants (< 61 days) with a first AOM episode.
- Analysis of demographic, clinical, and laboratory data from medical records.
- Comparison of diagnoses made by paediatricians and otolaryngologists.
Main Results:
- Respiratory symptoms (70.0%) and fever (62.5%) were common presenting signs.
- Streptococcus pneumoniae and Haemophilus influenzae were the most frequent pathogens; Gram-negative bacilli in 10.5%.
- Paediatricians diagnosed only 45% of AOM cases later confirmed by otolaryngologists; high leukocyte count did not reliably predict bacterial infection.
Conclusions:
- Absence of reliable predictors for bacterial infection in over 70% of bacterial AOM cases supports empirical antibiotic use in young infants, even without fever or abnormal labs.
- Low diagnostic rate by paediatricians highlights the need for enhanced examination skills and instrumentation for accurate AOM diagnosis in very young children.
Objective:
To assess the clinical and laboratory features of acute otitis media (AOM) in infants younger than 2 months, to look for factors predicting bacterial otitis, and to evaluate the accuracy of AOM diagnosis among paediatricians.
Methods:
The study population comprised a cohort of 277 hospitalised infants up to 61 days old that were treated for the first episode of AOM in a paediatric department. We reviewed their medical records and analysed the demographic, clinical and laboratory data, and the diagnosis made by both paediatricians and otolaryngologists.
Results:
Presenting symptoms were mainly respiratory (70.0%) and fever (62.5%). The most common pathogens were Streptococcus pneumoniae and Haemophilus influenzae. Gram-negative bacilli grew in 10.5% of the infants. Multivariate analysis revealed that AOM in the second month of life was associated with male gender, concurrent bronchiolitis and diarrhea. Although high leukocyte count was associated with bacterial pathogen, more than 70% of the patients with positive culture had normal white blood cell counts. The paediatrician diagnosed only 45% of the patients subsequently diagnosed with AOM by an otolaryngologist.
Conclusions:
The absence of predictors for bacterial infection in more than 70% of bacterial AOM suggests that empirical antibiotic treatment should be advised for the young infants with AOM even when afebrile and with normal laboratory profile. A low diagnostic rate of AOM by the paediatrician emphasizes the need for improvement in examination skills and instrumentation to allow a thorough ear evaluation in children of a very young age.
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