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Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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Related Experiment Video

Updated: Jul 6, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
10:10

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

[Pulmonary and osteoarticular tuberculosis].

Anabela Barcelos1, Aida Coelho, Filomena Freitas

  • 1Unidade de Reumatologia, Hospital Infante D Pedro, EPE, Aveiro, Portugal. barcelos.a@clix.pt

Acta Reumatologica Portuguesa
|March 18, 2008
PubMed
Summary

Tuberculosis is a growing global health concern, often linked to AIDS. This case highlights simultaneous pulmonary and osteoarticular tuberculosis, demonstrating the disease

Area of Science:

  • Infectious Diseases
  • Public Health
  • Medical Case Study

Background:

  • Tuberculosis (TB) is a significant infectious disease with increasing global prevalence, exacerbated by the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) epidemic.
  • While primarily recognized as a pulmonary condition, TB can disseminate via lymphohematogenous routes to affect virtually any organ system, including the nervous, genitourinary, gastrointestinal, and musculoskeletal systems.

Observation:

  • This report details a specific case where a patient presented with concurrent manifestations of both pulmonary tuberculosis and osteoarticular tuberculosis.
  • The simultaneous diagnosis underscores the systemic potential of Mycobacterium tuberculosis infection.

Findings:

  • The case successfully demonstrates the simultaneous occurrence of tuberculosis affecting both the lungs and the bone and joint structures.

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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

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A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
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  • Diagnostic confirmation involved integrated assessment of pulmonary and osteoarticular involvement.

    • Implications:

    • This case emphasizes the importance of considering extrapulmonary tuberculosis, particularly osteoarticular involvement, even when pulmonary disease is present.
    • Clinicians should maintain a high index of suspicion for disseminated tuberculosis in patients with risk factors such as HIV/AIDS.
    • Comprehensive diagnostic approaches are crucial for timely identification and management of multi-systemic tuberculosis.