[Heterozygote carrier state of hemoglobin S in Azerbaijan]

Clinico-hematological characteristics of 123 HbS heterozygotes have been presented. A total of 16 subjects with the level of HbS less than 30% were detected. Intraerythrocytic inclusions observed in single cells, as well as a significant decrease in the mean hemoglobin level, ESR and mean cell hemoglobin denote the presence of concomitant alpha-thalassemia-I in this group of heterozygotes. A comparative evaluation of phenotypic manifestations depending on HbS level has been presented. It is shown that shifts in the relative content of HbS lead to the widening of the borders of phenotypic manifestations.