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Related Experiment Video

Updated: Jul 6, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Published on: June 2, 2014

Managing headache during pregnancy and lactation.

Dawn A Marcus1

  • 1Pain Evaluation & Treatment Institute, 5750 Centre Avenue, Pittsburgh, PA 15206, USA. marcusd@upmc.edu

Expert Review of Neurotherapeutics
|March 19, 2008
PubMed
Summary

Pregnancy often changes headache patterns, with most migraines improving. However, effective clinical care, including safe treatments, is crucial for pregnant women with persistent headaches to protect the baby.

Area of Science:

  • Neurology
  • Obstetrics
  • Pharmacology

Background:

  • Headache prevalence and characteristics are altered during pregnancy for both primary and secondary headache disorders.
  • Migraine improvement is common in pregnancy, affecting approximately two-thirds of women.
  • Persistent headaches during pregnancy necessitate specialized medical attention.

Purpose of the Study:

  • To review the epidemiology of headaches during pregnancy and lactation.
  • To examine the impact of pregnancy and lactation on headache activity.
  • To discuss concerns regarding maternal headache diagnoses and pregnancy outcomes.

Main Methods:

  • Literature review focusing on headache epidemiology in pregnant and lactating populations.
  • Analysis of diagnostic and therapeutic challenges during pregnancy and breastfeeding.

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  • Synthesis of current evidence on management strategies.
  • Main Results:

    • Pregnancy influences headache patterns, with a majority of migraines showing improvement.
    • A significant minority of women experience ongoing or new-onset headaches during pregnancy.
    • Evidence-based guidelines for safe diagnostic and therapeutic interventions are presented.

    Conclusions:

    • Effective management of headaches during pregnancy requires careful consideration of fetal and infant safety.
    • Modified diagnostic approaches and therapeutic regimens are essential for pregnant women with headaches.
    • This review provides a framework for clinical care, balancing maternal health with minimized risks to the baby.