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A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
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A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Carotid stenting: risk factors for periprocedural stroke

Kamaldeep S Heyer1, Mark K Eskandari

  • 1Northwestern University, Division of Vascular Surgery, 201 East Huron Street, Galter 10-105, Chicago, IL 60611, USA.

Expert Review of Neurotherapeutics
|March 19, 2008
PubMed

Insights

Carotid artery stenting offers a minimally invasive option for stroke prevention. This review identifies key factors like interventionalist skill, patient health, and device design that influence stroke risk during the procedure.

Area of Science:

  • Interventional Cardiology
  • Neurology
  • Vascular Surgery

Background:

  • Carotid artery stenting (CAS) is a minimally invasive alternative to carotid endarterectomy for cervical carotid artery occlusive disease.
  • Despite advancements, periprocedural stroke risk remains a significant concern in CAS.
  • Identifying risk factors is crucial for improving patient outcomes.

Purpose of the Study:

  • To review technical, clinical, and radiographic factors associated with increased stroke risk during carotid artery stenting.
  • To highlight predictors of poorer outcomes in CAS procedures.

Main Methods:

  • Literature review of technical, clinical, and radiographic factors.
  • Analysis of patient comorbid conditions (diabetes, coronary artery disease, renal failure, advanced age).
  • Evaluation of equipment factors (embolic protection systems, stent designs).

Main Results:

  • Technical proficiency of the interventionalist is a key factor.
  • Patient comorbidities significantly impact stroke risk.
  • Specific equipment designs and embolic protection systems influence outcomes.

Conclusions:

  • Understanding these risk factors can help mitigate periprocedural stroke risk in CAS.
  • Optimizing technique, patient selection, and device choice are essential for safe and effective carotid artery stenting.

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