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Updated: Jul 6, 2026

A 3D Cartographic Description of the Cell by Cryo Soft X-ray Tomography
Published on: March 15, 2021
Do we need molecular tomography of a cell and how can it be achieved?
Yi-Zhang Chen1, Xiao-Ping Chen
1Institute of Neuroscience, Second Military Medical University, Shanghai, China. yzchen0928@yahoo.com
Abstract:
1. The spatial relationship between intracellular molecules and their local concentrations are two critical parameters required for a better understanding of protein-protein interactions in the cell. 2. Determination of the local concentration of proteins in individual cells using more sophisticated techniques and determination of the spatial relationship between a molecular platform and its partners is essential for allow us to obtain more convincing and concrete scientific conclusions. 3. As a reasonable goal, development of molecular tomography of the cell is proposed.
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