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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Primary multifocal osseous Hodgkin's lymphoma
Clare R Langley1, Simon J W Garrett, Jill Urand
1Orthopaedic Department, Basingstoke and North Hampshire Foundation Trust, Aldermaston Road, Basingstoke, Hampshire, RG24 9NA, UK. clarelangley@hotmail.com
Background:
Hodgkin's disease (HD) most commonly presents with progressive painless enlargement of peripheral lymph nodes, especially around the cervical region. A few children have systemic symptoms and weight loss. At the time of diagnosis, osseous involvement is uncommon
Case Presentation:
A case is described of Primary Multifocal Osseous Hodgkin's Lymphoma in a seven-year-old boy. He presented with a painful swelling in the sternum, and further investigations revealed deposits in his L1 vertebra, the left sacro-iliac joint and the right acetabulum.
Conclusion:
The clinical, radiological and histological features of this disease can mimic other medical conditions, including Tuberculosis, making the diagnosis difficult and often leading to delays in treatment. This is a very rare condition and we believe this to be the youngest reported case in the literature.
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