Methicillin-resistant Staphylococcus aureus--positive surgical site infections in face-lift surgery

Richard A Zoumalan1, David B Rosenberg

  • 1Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, Lennox Hill-Manhattan Eye, Ear, and Throat Hospital, NY, NY, USA.

Abstract

Insights

Methicillin-resistant Staphylococcus aureus (MRSA) surgical site infections occurred in 0.6% of face-lift patients. This highlights the need for improved MRSA screening, prevention, and treatment strategies in plastic surgery.

Area of Science:

  • Plastic Surgery
  • Infectious Disease Epidemiology
  • Surgical Site Infections

Background:

  • Surgical site infections (SSIs) are a significant concern in aesthetic surgery.
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a prevalent pathogen causing difficult-to-treat infections.
  • The incidence of MRSA SSIs after face-lift surgery is not well-documented.

Observation:

  • A retrospective review of 780 face-lift (deep-plane rhytidectomy) patients between 2001 and 2007 was conducted.
  • Five patients (0.6%) developed SSIs, with four testing positive for MRSA.
  • Two severe MRSA infections required hospitalization, drainage, and IV/oral antibiotics, while two responded to oral antibiotics and local care.

Findings:

  • The incidence of MRSA-positive SSIs after face-lift surgery was 0.5% (4 of 780 patients).
  • Complicated MRSA infections occurred on postoperative days 5 and 8.
  • Patients with complicated infections had recent healthcare or physician contact.

Implications:

  • MRSA SSIs pose an increasing challenge in plastic surgery, blurring community- and healthcare-associated distinctions.
  • Effective screening, prevention, and treatment protocols are crucial for managing MRSA in aesthetic procedures.
  • Future strategies must address the rising prevalence of MRSA in surgical settings.

Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Mechanism of Antibiotic Resistance in MRSA01:25

Mechanism of Antibiotic Resistance in MRSA

Antibiotic resistance in bacteria arises when microorganisms evolve the ability to withstand drugs designed to kill them or inhibit their growth, rendering once-effective treatments useless. This phenomenon, driven by genetic change and selection under antibiotic exposure, poses a profound threat to modern medicine. Mechanisms include drug-inactivating enzymes (e.g., β-lactamases), efflux pumps that eject antibiotics, mutations altering antibiotic targets, decreased drug uptake, and acquisition...