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A new thiaziedione from the fruits of Xanthium sibiricum

Ying-Hui Dai1, Zheng Cui, Jian-Lin Li

  • 1School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.

Journal of Asian Natural Products Research
|March 19, 2008
PubMed

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Antihypertensive Drugs: Thiazide-Class Diuretics01:15

Antihypertensive Drugs: Thiazide-Class Diuretics

Thiazide diuretics are sulfonamide derivatives featuring a benzothiadiazine ring system in their molecular structure. Based on this structure, thiazide diuretics can be categorized into two groups: thiazide-type and thiazide-like diuretics. Thiazide-type diuretics, including hydrochlorothiazide and chlorothiazide, consist of a benzothiadiazine backbone with an attached sulfonamide group. Thiazide-like diuretics, such as chlorthalidone and indapamide, lack the thiazide ring but demonstrate...