Outpatient laparoscopic management of ectopic pregnancy with a local methotrexate injection

Nine patients with unruptured tubal ectopic gestations were treated as outpatients utilizing a laparoscopically directed injection of methotrexate into the tubal mass. The initial quantitative serum human chorionic gonadotropin values ranged from 34 to 17,100 mIU/mL. Eight of nine subjects had complete resolution of the pregnancy over the ensuing 10-33 days; the remaining patient, with plateauing human chorionic gonadotropin levels, required a laparotomy.