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Balamuthia mandrillaris resistance to hostile conditions
Ruqaiyyah Siddiqui1, Antonio Ortega-Rivas2, Naveed Ahmed Khan1
1School of Biological and Chemical Sciences, Birkbeck College, University of London, London WC1E 7HX, UK.
Abstract:
The resistance of Balamuthia mandrillaris to physical, chemical and radiological conditions was tested. Following treatments, viability was determined by culturing amoebae on human brain microvascular endothelial cells for up to 12 days. B. mandrillaris cysts were resistant to repeated freeze-thawing (five times), temperatures of up to 70 degrees C, 0.5 % SDS, 25 p.p.m. chlorine, 10 microg pentamidine isethionate ml(-1) and 200 mJ UV irradiation cm(-2).
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