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Amyloid-beta-related angiitis: a rare cause of recurrent transient neurological symptoms
Amy Amick1, Jeff Joseph, Nicholas Silvestri
1Beth Israel Deaconess Medical Center, Department of Neurology, Boston, MA 02215, USA. aamick@bidmc.harvard.edu
Background:
A 79-year-old woman presented with transient right-sided weakness. She subsequently developed further transient neurological signs and symptoms across a range of vascular territories. Diagnostic workup revealed no clear etiology. The patient developed a sudden, fatal intracerebral hemorrhage, and the diagnosis was only revealed at autopsy.
Investigations:
Neurological examination, head CT, brain MRI, fluid-attenuated inversion recovery imaging, magnetic resonance angiography, lumbar puncture, CT angiography, electroencephalography, and brain autopsy.
Diagnosis:
Amyloid-beta-related angiitis.
Management:
The patient expired before treatment could be initiated. Immunosuppressants are recommended for future cases.
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