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Updated: Jul 6, 2026

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

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[HIFU in urological oncology].

S Thüroff¹, C Chaussy

¹Urologische Klinik, Klinikum Harlaching, Sanatoriumsplatz 2, 81545 München, Deutschland. sthueroff@mnet-online.de

Der Urologe. Ausg. A

|March 21, 2008

Summary

High-intensity focused ultrasound (HIFU) offers a noninvasive therapeutic option for prostate cancer, with ongoing research for kidney cancer applications. Current European practice utilizes HIFU for prostate cancer, showing promise for various tumor types and recurrences.

Area of Science:

Oncological therapies
Medical physics
Urological treatments

Background:

High-intensity focused ultrasound (HIFU) is emerging as a significant noninvasive therapeutic modality.
Its application in urological oncology includes transrectal treatment for prostate cancer and extracorporeal treatment for kidney cancer.

Purpose of the Study:

To review the current applications and efficacy of HIFU in urological oncology.
To highlight the established use of HIFU in prostate cancer treatment and its developing role in kidney cancer.

Main Methods:

Review of monocentric, prospective clinical studies on HIFU for prostate cancer.
Analysis of published results from different HIFU devices used in clinical practice.

Main Results:

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Real-time Monitoring of High Intensity Focused Ultrasound (HIFU) Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound (HMIFU)

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HIFU is utilized in daily European practice for prostate cancer treatment.
Published results indicate HIFU is effective for well-differentiated and moderately differentiated prostate tumors, and local recurrence post-radiation.
Two distinct transrectal HIFU devices exist with differing technologies, applications, outcomes, and side effects.
Early results for HIFU in locally recurrent or advanced/metastatic disease show promise in reducing morbidity and delaying progression.

Conclusions:

HIFU is a valuable treatment option for specific prostate cancer indications.
Further clinical feasibility studies are needed for kidney cancer applications.
Ongoing research explores HIFU's potential in managing locally advanced and recurrent urological malignancies.