Complete cranium bifidum without scalp abnormality. Case report
1Department of Neurosurgery, Beyoglu State Hospital, Istanbul, Turkey. suaterolcelik@yahoo.com
Journal of Neurosurgery. Pediatrics
|March 21, 2008
Summary
This study reports the first case of complete cranium bifidum in a newborn without other congenital anomalies. The rare cranial defect persisted for 3 years, suggesting a potential coincidental mutation.
Area of Science:
- Neonatal pathology
- Developmental biology
- Medical genetics
Background:
- Cranium bifidum is a rare congenital anomaly in newborns.
- Most cases involve enlarged parietal foramina and additional abnormalities.
- This condition requires detailed investigation due to its rarity.
Observation:
- Presents the first reported case of complete cranium bifidum.
- The infant had no other associated congenital anomalies.
- The cranial defect remained present throughout a 3-year follow-up period.
Findings:
- Complete cranium bifidum occurred as an isolated anomaly.
- No hereditary or familial links were identified.
- The isolated presentation suggests a possible de novo mutation.
Implications:
- Highlights the spectrum of cranium bifidum presentations.
- Suggests that isolated complete cranium bifidum may arise from spontaneous genetic events.
- Contributes to understanding rare neonatal cranial defects and their etiology.
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