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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Skin Cancer

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Related Experiment Video

Updated: Jul 6, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Granuloma faciale.

A Khaled1, M Jones, R Zermani

  • 1Department of Dermatology, Charles Nicolle Hospital of Tunis. aida.khaled@rns.tn

Pathologica
|March 22, 2008
PubMed
Summary
This summary is machine-generated.

Granuloma faciale is a rare skin condition presenting as a facial lesion. Pulsed-dye laser therapy effectively treated a case, highlighting its utility for this benign dermatosis.

Related Experiment Videos

Last Updated: Jul 6, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Granuloma faciale is a rare, benign, and typically isolated skin condition.
  • It commonly affects the face but can occur in extrafacial sites.
  • Differential diagnosis includes benign and malignant dermatoses.

Observation:

  • A 49-year-old male presented with a 6-month history of an asymptomatic, 10 mm, red-brown papulo-nodular lesion on the nose.
  • Histopathological examination confirmed the diagnosis of granuloma faciale.

Findings:

  • The patient underwent a single session of pulsed-dye laser therapy.
  • Significant clinical improvement was observed following the treatment.

Implications:

  • This case illustrates the clinical and histological features of granuloma faciale.
  • Pulsed-dye laser therapy is an effective treatment option for granuloma faciale.
  • Accurate diagnosis is crucial to differentiate from other skin conditions.