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Updated: Jul 6, 2026

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Distraction osteogenesis for temporomandibular joint reconstruction
Harry C Schwartz1, Robert J Relle
1Southern California Permanente Medical Group, Oral and Maxillofacial Surgery, University of California Los Angeles, Los Angeles, CA, USA. HCSchwartz@scal.kp.org
Purpose:
This clinical study evaluated the use of transport distraction osteogenesis in reconstruction of the ramus-condyle unit (RCU) of the temporomandibular joint (TMJ).
Patients And Methods:
Thirteen TMJ reconstructions were carried out in 12 patients. Diagnoses included tumors, trauma, ankylosis, and degenerative joint disease. The follow-up period has ranged from 7 to 59 months.
Results:
Successful distraction was carried out in all cases, with development of solid regenerate bone and an effective new articulation. There were no complications. A good functional level was achieved in all cases. One patient with bilateral rheumatoid arthritis has experienced ongoing degenerative changes in the reconstructed condyles, with reappearance of an anterior open bite. The occlusion has remained stable in all other cases.
Conclusions:
Distraction osteogenesis is a promising treatment option in reconstruction of the RCU of the TMJ.
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