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Updated: Jul 6, 2026

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions
Published on: February 9, 2024
Hypervascular thyroid nodules on time-resolved MR angiography at 3 T: radiologic-pathologic correlation.
Derek G Lohan1, Anderanik Tomasian, Roya Saleh
1Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Peter V. Ueberroth Bldg., Ste. 3371, 10945 Le Conte Ave., Los Angeles, CA 90095-7206, USA. derek.lohan@gmail.com
Focal hyperenhancing thyroid nodules found incidentally during time-resolved MR angiography have a significant malignancy rate of 8.3%. Further investigation is recommended for these thyroid lesions.
Area of Science:
- Radiology
- Endocrinology
- Oncology
Background:
- Thyroid nodules are common, often causing diagnostic uncertainty.
- Tissue sampling is definitive for characterization, but imaging may suggest malignancy.
- Time-resolved MR angiography (MRA) is valuable for vascular imaging.
Purpose of the Study:
- To determine the frequency and significance of focal hyperenhancing thyroid nodules found during time-resolved MRA.
- To assess the malignancy potential of these incidentally detected lesions.
Main Methods:
- Retrospective review of time-resolved MRA scans.
- Identification of incidentally detected focal hyperenhancing thyroid nodules.
- Pathologic correlation (cytology) where available.
Main Results:
- Focal hyperenhancing thyroid nodules were identified during time-resolved MRA.
- Malignancy prevalence was 8.3% (1/12) in patients with cytologic correlation.
- Time-resolved MRA did not aid in differentiating benign from malignant lesions.
Conclusions:
- Incidental focal hyperenhancing thyroid nodules on time-resolved MRA have a notable malignancy risk.
- Further investigation is warranted for these findings.
- Time-resolved MRA is not sufficient for pathologic discrimination of these nodules.
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