Related Experiment Video
Updated: Jul 6, 2026
05:56
Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit
Published on: September 6, 2024
Inductive plethysmography to control volume-targeted ventilation for leak compensation
Marie Claire Andrieu1, Cedric Quentin, David Orlikowski
1Saime-ResMed Corporation, Savigny le Temple, France.
Intensive Care Medicine
|March 22, 2008
Summary
New ventilator technology effectively compensates for leaks during volume-targeted ventilation, improving delivery for patients with neuromuscular conditions. Both feedback methods showed promise in managing inspiratory and expiratory leaks.
Area of Science:
- Respiratory physiology
- Biomedical engineering
Background:
- Volume-targeted ventilation (VTV) is crucial for patients with neuromuscular weakness.
- VTV struggles with leak compensation, particularly mouth leaks common in these patients.
- Existing VTV systems may deliver inaccurate volumes with leaks.
Purpose of the Study:
- To assess the feasibility and efficacy of a prototype VTV system with leak compensation.
- To compare two feedback control methods: volume blown to the expiratory circuit (VTEVC-compensation) and inductive plethysmography (VTplet-compensation).
Main Methods:
- A randomized, cross-over physiological study was conducted.
- Nine healthy individuals participated.
- Ventilation was tested with no compensation, VTEVC-compensation, and VTplet-compensation under various leak conditions (mouth closed, inspiratory leak, expiratory leak).
Main Results:
- Without compensation, inspiratory leaks significantly reduced expired tidal volume.
- Both VTEVC-compensation and VTplet-compensation improved expired tidal volume during inspiratory leaks.
- VTplet-compensation effectively managed both inspiratory and expiratory leaks, while VTEVC-compensation showed an increase in delivered volume with expiratory leaks.
Conclusions:
- Leak compensation is achievable in VTV systems.
- VTEVC-compensation and VTplet-compensation demonstrated comparable efficacy for inspiratory leaks.
- VTplet-compensation showed superior performance in managing both inspiratory and expiratory leaks.
Related Concept Videos
01:14Ventilatory Modes
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
01:23Mechanical Ventilation II: Invasive Ventilation
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
01:29Mechanical Ventilation I: Indication and Settings
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
01:23Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)
Noninvasive Positive-Pressure Ventilation (NIPPV)
01:15Respiratory Volumes
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
01:24Pulmonary Ventilation: Inhalation
Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
Boyle's law becomes particularly pertinent when examining respiratory...