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Updated: Jul 6, 2026
11:32
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
[Invasive pneumococcal disease and hemolytic uremic syndrome].
A Fàbregas Martori1, F Moraga-Llop, J Nieto Rey
1Unidad de Enfermedades Infecciosas, Hospital Universitario Vall d'Hebron, Universidad Autónoma de Barcelona, Barcelona, Spain.
Anales De Pediatria (Barcelona, Spain : 2003)
|March 25, 2008
Summary
Streptococcus pneumoniae can cause severe hemolytic uremic syndrome (HUS). Prompt diagnosis of pneumococcal invasive disease is crucial for managing this severe HUS complication.
Area of Science:
- Nephrology
- Infectious Diseases
- Pulmonology
Background:
- Streptococcus pneumoniae is an uncommon cause of hemolytic uremic syndrome (HUS).
- Pneumococcal-associated HUS can be more severe than typical HUS cases.
Observation:
- Two patients with pneumococcal pneumonia and empyema developed HUS.
- One patient experienced renal function recovery, while the other required a kidney transplant.
Findings:
- Invasive pneumococcal disease is a potential cause of severe HUS.
- Clinical presentation and outcomes vary among affected individuals.
Implications:
- A high index of suspicion for pneumococcal invasive disease is essential in HUS cases.
- Early diagnosis and management are critical for improving patient outcomes in severe HUS.
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