Related Experiment Videos
Pityrosporum ovale/orbiculare in papillomatous nevus cell nevi
1Abteilung Dermatologie mit Schwerpunkt Histopathologie und Elektronenmikroskopie der Haut, Philipps-Universität, Marburg, BRD.
Abstract:
62% of 200 papillomatous nevus cell nevi compared to 45% of 40 seborrheic keratoses showed the presence of Pityrosporum ovale/orbiculare (Malassezia furfur) on their surface, supposedly representing a saprophytic state of the microorganisms in vivo. The papillomatous nevus cell nevi were of the compound or dermal type. Significant inflammation, dysplasia or major changes in color were absent. Electron microscopy revealed the characteristic, sometimes budding fungal cells. A relationship between the presence of Pityrosporum organisms and papillomatosis is discussed.
Insights
Pityrosporum ovale/orbiculare (Malassezia furfur) fungi were found on 62% of papillomatous nevus cell nevi, suggesting a saprophytic state. This finding may indicate a relationship between these fungi and papillomatosis.
Area of Science:
- Dermatology
- Mycology
- Pathology
Background:
- Papillomatous nevus cell nevi are benign skin growths.
- The presence of microorganisms on skin lesions is often investigated for potential associations.
- Pityrosporum ovale/orbiculare (Malassezia furfur) is a common yeast found on human skin.
Purpose of the Study:
- To investigate the presence and potential role of Pityrosporum ovale/orbiculare (Malassezia furfur) on papillomatous nevus cell nevi.
- To compare the prevalence of these fungi on nevus cell nevi versus seborrheic keratoses.
- To explore a possible relationship between Pityrosporum organisms and papillomatosis.
Main Methods:
- Microscopic examination of 200 papillomatous nevus cell nevi and 40 seborrheic keratoses.
- Identification of Pityrosporum ovale/orbiculare (Malassezia furfur) on lesion surfaces.
- Electron microscopy to visualize fungal cells.
Main Results:
- Pityrosporum ovale/orbiculare (Malassezia furfur) was detected on 62% of papillomatous nevus cell nevi and 45% of seborrheic keratoses.
- The fungi were observed in a saprophytic state.
- Electron microscopy confirmed the presence of fungal cells, including budding forms.
- No significant inflammation, dysplasia, or major color changes were noted in the affected nevi.
Conclusions:
- The high prevalence of Pityrosporum ovale/orbiculare (Malassezia furfur) on papillomatous nevus cell nevi suggests a potential association.
- The findings support the hypothesis of a saprophytic relationship between these fungi and the skin lesions.
- Further research is warranted to elucidate the precise relationship between Pityrosporum organisms and papillomatosis.