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Updated: Jul 6, 2026

15:01
Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons
Published on: August 6, 2012
Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons
Kenneth J Oh1, Kevin J Cash, Arica A Lubin
1Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. oh@chem.ucsb.edu
Abstract:
We have developed a new biosensor architecture, which is comprised of a polypeptide-peptide nucleic acid tri-block copolymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.
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