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Related Experiment Video

Updated: Jul 6, 2026

Isolation of Atrial Myocytes from Adult Mice

Isolation of Atrial Myocytes from Adult Mice

Published on: July 25, 2019

[Natriuretic peptides in clinical practice].

Roman Urek¹, Mirjana Cubrilo-Turek

¹University Department of Cardiovascular Diseases, School of Medicine, University of Zagreb, Sveti Duh General Hospital, Zagreb, Croatia.

Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti

|March 28, 2008

Summary

The natriuretic peptide (NP) system, including atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), is vital for cardiovascular health. Elevated NP levels signal cardiac risk and aid in diagnosing heart conditions.

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Isolation of Atrial Myocytes from Adult Mice

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Published on: August 2, 2024

Area of Science:

Endocrinology
Cardiovascular Physiology

Context:

The natriuretic peptide (NP) system regulates fluid and pressure homeostasis.
Cardiac NPs, ANP and BNP, are secreted by the heart based on cardiac transmural pressures.

Purpose:

To highlight the role of NPs as biomarkers for cardiac health.
To discuss the diagnostic and prognostic applications of NPs in cardiovascular disorders.

Summary:

Plasma NP levels correlate with cardiac load, serving as early indicators of cardiac events.
BNP and NT-BNP are sensitive markers for cardiac dysfunction, remodeling, and coronary artery disease detection.
NPs like carperitide and nesiritide are used therapeutically for acute decompensated heart failure.

Impact:

NP measurements offer valuable insights into cardiovascular status.
Therapeutic applications of NPs improve management of heart failure.
Early detection of cardiac risk through NP levels can guide clinical interventions.