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Related Experiment Video

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Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches

Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches

Published on: October 17, 2019

A muscle transcriptome analysis identifies positional candidate genes for a complex trait in pig.

V Lobjois¹, L Liaubet, M SanCristobal

¹INRA UMR444 Génétique Cellulaire, 31326 Castanet-Tolosan, France.

Animal Genetics

|March 28, 2008

Summary

Gene expression variability is linked to muscle tenderness in pigs. This study identified specific genes associated with meat quality traits, aiding genetic improvement in animal breeding.

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Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches

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Published on: October 17, 2019

Identification of Coding and Non-coding RNA Classes Expressed in Swine Whole Blood

Identification of Coding and Non-coding RNA Classes Expressed in Swine Whole Blood

Published on: November 28, 2018

Area of Science:

Animal Genetics
Molecular Biology
Meat Science

Background:

Muscle tenderness is a key trait for meat quality and animal breeding, but its genetic and physiological underpinnings are not fully understood.
Understanding gene expression's role in tenderness can lead to improved breeding strategies for enhanced meat quality.

Purpose of the Study:

To investigate the relationship between gene expression variability and muscle tenderness in pigs.
To identify candidate genes associated with muscle tenderness for potential use in genetic improvement programs.

Main Methods:

Transcriptome analysis of longissimus dorsi muscle samples from 30 F2 pigs.
Measurement of muscle tenderness using Warner-Bratzler Shear Force (WBSF).
Linear regression analysis to associate gene expression levels with WBSF values.

Main Results:

A significant association was found between gene expression levels and shear force in samples with WBSF > 30 N.
Identified genes involved in cell cycle, energy metabolism, and muscle development networks.
Twelve candidate genes were mapped to known quantitative trait loci (QTL) regions for pig meat tenderness on chromosomes 2, 6, and 13.

Conclusions:

Gene expression variability plays a role in determining muscle tenderness.
Identified positional candidate genes provide a basis for further research into the genetic control of meat quality.
Findings support the use of gene expression data in animal breeding for improving meat tenderness.