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Updated: May 24, 2026

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
Published on: October 25, 2015
[High epidural anesthesia as a component of anesthetic support for cardiosurgical interventions in infants]
Insights
Adding epidural anesthesia to anesthetic support for infant ventricular septal defect surgery reduced anesthetic dosage and ventilation time. This approach offers benefits for pediatric cardiac surgical patients.
Area of Science:
- Pediatric Cardiac Surgery
- Anesthesiology
- Critical Care Medicine
Background:
- Ventricular septal defect (VSD) is a common congenital heart defect requiring surgical correction.
- Anesthetic management for infant cardiac surgery aims to optimize hemodynamics and reduce stress response.
- Epidural anesthesia is increasingly explored as an adjunct in pediatric surgical procedures.
Purpose of the Study:
- To evaluate the efficacy and safety of incorporating epidural anesthesia into the anesthetic regimen for infant VSD repair.
- To compare outcomes between infants receiving standard total intravenous anesthesia and those with augmented epidural anesthesia.
Main Methods:
- Prospective, nonrandomized, monocenter case-control study involving 79 infants undergoing VSD repair.
- Control group (n=41): Total intravenous anesthesia with propofol and fentanyl.
- Study group (n=38): Anesthesia potentiated by high, prolonged epidural anesthesia.
Main Results:
- The study group demonstrated decreased intraoperative anesthetic dosage compared to the control group.
- Patients receiving epidural anesthesia required shorter durations of inotropic support.
- A significant reduction in the duration of postoperative mechanical ventilation was observed in the study group.
Conclusions:
- Integrating epidural anesthesia into the anesthetic support for infant VSD surgery is expedient.
- Epidural anesthesia can lead to reduced anesthetic requirements and improved postoperative recovery, including shorter ventilation times.
- This anesthetic strategy may enhance outcomes for infants undergoing surgical correction of ventricular septal defects.
Abstract:
The aim of the study was to determine whether it was expedient to include epidural anesthesia into a complex of anesthetic support of surgical correction of ventricular septal defect in infants. This was a prospective, nonrandomized, monocenter case-control study. Seventy-nine infants met the inclusion criteria. A control group included 41 patients in whom total intravenous anesthesia was based on the infusion of propofol and fentanyl; a study comprised 38 patients in whom anesthetic support was potentiated by high prolonged epidural anesthesia. In the study group patients, the total dosage of anesthetics and the duration of inotropic support decreased intraoperatively and there was a reduction in the duration of postoperative artificial ventilation.
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