Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

M-Cdk Drives Transition Into Mitosis

M-Cdk Drives Transition Into Mitosis

Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...

M-Cdk Drives Transition Into Mitosis

M-Cdk Drives Transition Into Mitosis

Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...

Interphase

Interphase

The cell cycle occurs over approximately 24 hours (in a typical human cell) and in two distinct stages: interphase, which includes three phases of the cell cycle (G1, S, and G2), and mitosis (M). During interphase, which takes up about 95 percent of the duration of the eukaryotic cell cycle, cells grow and replicate their DNA in preparation for mitosis.

Interphase

Interphase

The cell cycle occurs over approximately 24 hours (in a typical human cell) and in two distinct stages: interphase, which includes three phases of the cell cycle (G1, S, and G2), and mitosis (M). During interphase, which takes up about 95 percent of the duration of the eukaryotic cell cycle, cells grow and replicate their DNA in preparation for mitosis.
Phases of Interphase
Following each period of mitosis and cytokinesis, eukaryotic cells enter interphase, during which they grow and replicate...

Positive Regulator Molecules

Positive Regulator Molecules

Mitotic cell division results in daughter cells that exactly resemble the parent cell. However, errors in the DNA replication or distribution of genetic material may lead to genetic mutations that may be passed down to every new cell formed from the resulting abnormal cell. Propagation of such mutant cells is restricted through checkpoint mechanisms present at different stages of the cell cycle. These checkpoints involve regulator molecules that either promote or demote cell cycle events.

Positive Regulator Molecules

Positive Regulator Molecules

To consistently produce healthy cells, the cell cycle—the process that generates daughter cells—must be precisely regulated.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cleansing and Building in Rastafari Healing in London: Health Sovereignty for a Hostile Environment.

Medical anthropology·2025

Same author

Normalising intolerance: the efforts of Christian Right groups to block LGBTIQ+ inclusion in South African schools.

Culture, health & sexuality·2023

Same author

The cell cycle in plant development.

The New phytologist·2021

Same author

The effect of the slow-to-green mutation on cell division during leaf initiation and early leaf growth in Lolium temulentum.

The New phytologist·2021

Same author

Molecular Analysis of the E2F/DP Gene Family of <i>Daucus carota</i> and Involvement of the DcE2F1 Factor in Cell Proliferation.

Frontiers in plant science·2021

Same author

Queering the (Ab)Normalization of Gender, (Hetero)Sexuality and Schooling in South Africa.

Journal of homosexuality·2019

Same journal

Protein damage in the ageing process: advances in quantitation and the importance of enzymatic defences.

SEB experimental biology series·2009

Same journal

Atmospheric CO2 signalling, cellular redox state and plant growth and development.

SEB experimental biology series·2009

Same journal

Catalase regulation during leaf senescence of Arabidopsis.

SEB experimental biology series·2009

Same journal

Role of the glyoxalase pathway in delaying plant senescence under stress conditions.

SEB experimental biology series·2009

Same journal

A-type lamins, disease and ageing: a stress-induced relationship?

SEB experimental biology series·2009

Same journal

Telomeres, ageing and oxidation.

SEB experimental biology series·2009

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 6, 2026

Analysis of Cell Cycle Position in Mammalian Cells

Analysis of Cell Cycle Position in Mammalian Cells

Published on: January 21, 2012

The G2/M transition in eukaryotes

Dennis Francis¹

¹Cardiff School of Biosciences, Cardiff University, UK.

SEB Experimental Biology Series

|March 29, 2008

Summary

No abstract available in PubMed .

More Related Videos

Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy

Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy

Published on: June 24, 2019

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

Published on: March 22, 2018

Related Experiment Videos

Last Updated: Jul 6, 2026

Analysis of Cell Cycle Position in Mammalian Cells

Analysis of Cell Cycle Position in Mammalian Cells

Published on: January 21, 2012

Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy

Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy

Published on: June 24, 2019

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

Published on: March 22, 2018