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Updated: Jul 6, 2026

Microfluidic Mixers for Studying Protein Folding
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Microfluidic Mixers for Studying Protein Folding

Published on: April 10, 2012

Non-equilibrium electrokinetic micro/nano fluidic mixer.

Daejoong Kim1, Ankit Raj, Likun Zhu

  • 1Department of Mechanical Engineering, Sogang University, Seoul, S. Korea. daejoong@sogang.ac.kr

Lab on a Chip
|March 29, 2008
PubMed
Summary

We developed a novel micro/nano fluidic mixer using non-equilibrium electrokinetics. This mixer efficiently achieves mixing through vortex structures, offering a simple design for micro total analysis systems.

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Area of Science:

  • Microfluidics
  • Nanofluidics
  • Electrokinetics

Background:

  • Microfluidic devices are crucial for miniaturized systems.
  • Efficient mixing is a key challenge in microfluidics.
  • Non-equilibrium electrokinetics offers novel mixing strategies.

Purpose of the Study:

  • To propose and demonstrate a new micro/nano fluidic mixer.
  • To investigate mixing performance based on non-equilibrium electrokinetics.
  • To assess the device's suitability for micro total analysis systems.

Main Methods:

  • Fabrication of a micro/nano fluidic device using two-step reactive ion etching.
  • Generation of nanochannels and microchannels within the device.
  • Utilizing non-equilibrium electrokinetics to induce fluid motion.

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Main Results:

  • Successful fabrication of the micro/nano fluidic device.
  • Observation of strong vortex structures at the micro/nano channel interface.
  • Demonstration of efficient mixing performance attributed to these vortices.

Conclusions:

  • The proposed micro/nano fluidic mixer effectively utilizes non-equilibrium electrokinetics for mixing.
  • The device's simple design and fabrication present advantages for microfluidic applications.
  • This technology holds promise for advancing micro total analysis systems.