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Related Experiment Video

Updated: Jul 6, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

[Not Available].

M D Gutiérrez-Tarango1, A Berber

  • 1Pediatrics Service of `Pensiones Civiles del Estado de Chihuahua', Chihuahua City, Chihuahua, Mexico.

Clinical Drug Investigation
|February 1, 1997
PubMed
Summary
This summary is machine-generated.

Broncho-Vaxom, a bacterial extract, significantly reduced respiratory infections in children. This treatment led to fewer sick days and less need for antibiotics, offering a safe option for preventing recurrent respiratory issues.

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Area of Science:

  • Pediatrics
  • Immunology
  • Pharmacology

Background:

  • Recurrent respiratory tract infections (RRTIs) are a common concern in children.
  • Effective preventive strategies are needed to reduce the burden of RRTIs.

Purpose of the Study:

  • To evaluate the efficacy of bacterial extract OM-85 BV (Broncho-Vaxom) in preventing chronic, recurrent respiratory diseases in children.
  • To compare Broncho-Vaxom with conventional management for RRTIs.

Main Methods:

  • An open, prospective trial enrolled 61 children (1-11 years) with at least three RRTIs in six months.
  • The treatment group (30 children) received Broncho-Vaxom for three months, while the control group (31 children) received conventional management.
  • A six-month follow-up period monitored infection rates and treatment outcomes.

Related Experiment Videos

Last Updated: Jul 6, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

Main Results:

  • Children treated with Broncho-Vaxom experienced a significant reduction in the average number of infections (2.25 vs. 4.68).
  • The Broncho-Vaxom group had fewer days of illness (11.8 vs. 28.06), required fewer antibacterial treatments (1.1 vs. 2.52), and less additional conventional drug use (2.17 vs. 4.39).
  • Fewer treatment days were observed in the Broncho-Vaxom group (14.27 vs. 30).

Conclusions:

  • Broncho-Vaxom demonstrated significant efficacy in reducing the incidence of respiratory tract infections in susceptible children.
  • The bacterial extract is a practical and safe therapeutic option for preventing RRTIs.
  • This study supports the use of Broncho-Vaxom as an adjunct therapy in pediatric respiratory health.