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Identification of Neutrophil Extracellular Traps in Paraffin-Embedded Feline Arterial Thrombi using Immunofluorescence Microscopy
Published on: March 29, 2020
Portal vein thrombosis in cats: 6 cases (2001-2006)
C L Rogers1, T E O'Toole, J H Keating
1Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA, USA. catherine_l.rogers@tufts.edu
Journal of Veterinary Internal Medicine
|March 29, 2008
Summary
Portal vein thrombosis (PVT) in cats is often linked to underlying hepatic disease. This study examined clinical signs and associated conditions in six feline cases of PVT.
Area of Science:
- Veterinary Medicine
- Internal Medicine
- Diagnostic Imaging
Background:
- Portal vein thrombosis (PVT) is infrequently documented in feline medicine.
- Understanding concurrent conditions associated with PVT is crucial for diagnosis and treatment.
Purpose of the Study:
- To investigate the clinical presentation and co-existing diseases in cats diagnosed with portal vein thrombosis.
- To enhance the understanding of PVT's role in feline hepatic disease.
Main Methods:
- Retrospective review of medical records for six client-owned cats diagnosed with PVT via abdominal ultrasound or necropsy.
- Data collected included signalment, history, underlying disorders, clinical signs, clinicopathologic and histopathologic findings, diagnostic imaging, treatment, and outcomes.
Main Results:
- All six cats with PVT also presented with hepatic disease.
- Congenital portosystemic shunts were identified in three cats.
- Hepatic neoplasia was diagnosed in two cats, while one had acute cholangitis, pancreatitis, and hepatic necrosis.
- Thrombi were classified as acute in two cats and chronic in four cats.
Conclusions:
- Portal vein thrombosis may frequently occur concurrently with hepatic disease in cats.
- PVT should be considered in the diagnostic workup of cats with liver conditions.
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