Related Experiment Video

Updated: Jul 6, 2026

Direct Reprogramming of Mouse Fibroblasts into Melanocytes
09:38

Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Published on: August 27, 2021

c-Myc is dispensable for direct reprogramming of mouse fibroblasts

Marius Wernig, Alexander Meissner, John P Cassady

    Cell Stem Cell
    |March 29, 2008
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes09:16

    Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes

    Published on: June 3, 2018

    Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program11:00

    Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program

    Published on: December 16, 2016

    Related Concept Videos

    Induced Pluripotent Stem Cells01:06

    Induced Pluripotent Stem Cells

    Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
    Somatic cells are...
    Somatic to iPS Cell Reprogramming01:29

    Somatic to iPS Cell Reprogramming

    Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012 for this...
    Methods of Nuclear Reprogramming01:24

    Methods of Nuclear Reprogramming

    Nuclear reprogramming is a process of transforming one cell type into an unrelated cell type by epigenetic changes that alter the cell’s original gene expression pattern. Such epigenetic changes force cells to express a different set of genes, which play a significant role in inducing transformation into other cell types. Nuclear reprogramming offers applications in reproductive cloning for livestock propagation and regenerative medicine — developing patient-specific cells for injury repair.