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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

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Published on: January 29, 2018

Improved precision with Hologic Apex software.

B Fan1, E M Lewiecki, M Sherman

  • 1Department of Radiology, University of California, 185 Berry Street, Suite 350, San Francisco, CA 94107, USA. bo.fan@radiology.ucsf.edu

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
|April 1, 2008
PubMed
Summary
This summary is machine-generated.

Hologic Apex v2.0 software shows improved bone mineral density measurement precision compared to Delphi v11.2. Apex precision is comparable to GE Lunar Prodigy v7.5, enhancing diagnostic accuracy in dual-energy X-ray absorptiometry (DXA) scans.

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Area of Science:

  • Medical Imaging
  • Osteoporosis Diagnosis
  • Biomedical Engineering

Background:

  • Bone mineral density (BMD) measurement precision via dual-energy X-ray absorptiometry (DXA) varies by manufacturer and software.
  • Evaluating DXA analysis software precision is crucial for accurate osteoporosis diagnosis.
  • Technologist skill can influence DXA measurement variability.

Purpose of the Study:

  • To compare the precision of Hologic Apex v2.0 and Delphi v11.2 software.
  • To assess the precision of Hologic Apex v2.0 against GE Lunar Prodigy v7.5 software.
  • To evaluate DXA analysis software precision independent of technologist skill.

Main Methods:

  • Duplicate spine and hip DXA scans were performed on 90 women across three clinics.
  • Three analysis software versions were evaluated: Hologic Apex v2.0, Hologic Delphi v11.2, and GE Lunar Prodigy v7.5.
  • Precision errors were quantified using root-mean-square (RMS) standard deviations and coefficients of variation.

Main Results:

  • Hologic Apex v2.0 demonstrated significantly lower precision error than Delphi v11.2 across spine and hip measurements.
  • Apex v2.0 precision error was comparable to GE Lunar Prodigy v7.5, with no significant differences except for the right femoral neck.
  • High correlation (r=0.90-0.99) was observed between Apex and Delphi analysis results.

Conclusions:

  • Hologic Apex v2.0 software offers significantly improved precision over Delphi v11.2.
  • Apex v2.0 exhibits comparable precision to GE Lunar Prodigy v7.5.
  • These findings suggest enhanced accuracy for bone mineral density assessments using Apex v2.0.