Olfactory receptor trafficking to the plasma membrane

C F Bush1, R A Hall

  • 1Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
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Sec61 protein conducting channel
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