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Updated: Jul 6, 2026

Programmed Electrical Stimulation in Mice
Published on: May 26, 2010
Pseudo pacemaker stimuli
Matthew P Smelley1, Rory Childers, Bradley P Knight
1Section of Cardiology, Department of Internal Medicine, University of Chicago, Chicago, Illinois 60637, USA.
Abstract:
Current electrocardiographic technology is limited in its ability to detect pacemaker stimuli secondary to the use of 150 Hz low-pass bandwidth filters designed to block high-frequency interference. Software solutions to improve the sensitivity of pacemaker stimulus detection are associated with imperfect specificity. The following case reports include three patients who do not have a pacing device, but were identified by a computer-based preliminary interpretation of a routine 12-lead surface electrocardiogram (ECG) as having a paced rhythm.
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