[Acral lichen sclerosus et atrophicus]

Area of Science:

• Dermatology
• Pathology

Background:

• Lichen sclerosus et atrophicus (LS&A) is a chronic inflammatory skin condition.
• LS&A typically affects the anogenital region but can present with extragenital manifestations.
• Extremity involvement is uncommon and usually occurs with widespread cutaneous disease.

Observation:

• A 56-year-old woman presented with characteristic ivory white papules on her hands and feet.
• Lesions included keratotic papules on the palms and erythema on the soles.
• Genital and perigenital LS&A was also diagnosed.

Findings:

• Histopathological examination of lesions from both extremities and the genital area confirmed typical features of LS&A.
• This case represents a rare instance of LS&A predominantly affecting the extremities and genital region.

Implications:

• This case expands the recognized clinical presentation of lichen sclerosus et atrophicus.
• It underscores the importance of considering LS&A in cases of isolated extremity or combined extremity-genital skin lesions.
• Further research may elucidate specific triggers or predispositions for this pattern of LS&A.