Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 6, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Altered pain processing in children with migraine: an evoked potential study.

Katrin Zohsel1, Johanna Hohmeister, Herta Flor

  • 1Department of Clinical and Cognitive Neuroscience, Ruprecht-Karls-University of Heidelberg, Central Institute of Mental Health, Square J5 D-68159 Mannheim, Germany.

European Journal of Pain (London, England)
|April 1, 2008
PubMed
Summary

Children with migraine show an attentional bias towards painful stimuli. This altered processing of somatosensory stimuli may contribute to migraine chronicity in pediatric patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An eight-week placebo-controlled RCT on the efficacy of a probiotic nutritional intervention for subclinical gastrointestinal symptoms in students.

Scientific reports·2026
Same author

Structured Diagnostic Interviews in Psychotherapy Training: Trainees' Beliefs About Interviews and Their Relationship to Overall Interview Satisfaction.

Clinical psychology in Europe·2026
Same author

Placebo effects in a RCT assessing 30 days of low dose Cannabidiol (CBD) treatment for psychological distress in stressed students at risk for depression.

Journal of cannabis research·2025
Same author

Quantifying age-related disparities in outpatient psychotherapy utilization: a representation quotient analysis of routine data from 29 university clinics in Germany.

BMC health services research·2025
Same author

Correction: A Response to: Letter to the Editor Regarding "The Risk of Herpes Zoster in Patients with Depressive Disorders: A German Claims Database Analysis".

Infectious diseases and therapy·2025
Same author

A Response to: Letter to the Editor Regarding "The Risk of Herpes Zoster in Patients with Depressive Disorders: A German Claims Database Analysis".

Infectious diseases and therapy·2025

Area of Science:

  • Neuroscience
  • Pediatric Neurology
  • Pain Research

Background:

  • Migraine in adults is linked to altered pain processing and attention.
  • Understanding pain processing in pediatric migraine is crucial but limited.

Purpose of the Study:

  • To investigate altered pain processing and attentional mechanisms in children with migraine.
  • To compare somatosensory evoked potentials (SEPs) between children with and without migraine.

Main Methods:

  • An oddball standards task was used with 15 children with migraine and 15 controls (ages 10-15).
  • Participants responded to auditory targets while ignoring painful or non-painful mechanical stimuli.
  • Somatosensory evoked potentials (SEPs) and reaction times were recorded.

More Related Videos

Electrophysiological Measurement of Noxious-evoked Brain Activity in Neonates Using a Flat-tip Probe Coupled to Electroencephalography
06:29

Electrophysiological Measurement of Noxious-evoked Brain Activity in Neonates Using a Flat-tip Probe Coupled to Electroencephalography

Published on: November 29, 2017

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies
05:49

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

Published on: November 1, 2024

Related Experiment Videos

Last Updated: Jul 6, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Electrophysiological Measurement of Noxious-evoked Brain Activity in Neonates Using a Flat-tip Probe Coupled to Electroencephalography
06:29

Electrophysiological Measurement of Noxious-evoked Brain Activity in Neonates Using a Flat-tip Probe Coupled to Electroencephalography

Published on: November 29, 2017

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies
05:49

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

Published on: November 1, 2024

Main Results:

  • Both groups showed larger N150, P260, and P300 SEP components for painful versus non-painful stimuli.
  • Children with migraine exhibited larger P300 amplitudes and shorter latencies for both painful and non-painful stimuli.
  • No significant differences were found in pain perception, target evoked potentials, or habituation between groups.

Conclusions:

  • Children with migraine may have an automatic attentional bias towards somatosensory stimuli, including painful ones.
  • This attentional bias could be a key mechanism in the development of chronic migraine in pediatric populations.
  • Findings support the psychobiological perspective of chronic pain in understanding migraine.