Related Experiment Video
Updated: Jul 6, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Necrotizing systemic sarcoidosis with pulmonary and central nervous system involvement]
R Ríos Fernández1, J L Callejas-Rubio, M Guerrero Fernández
1Unidad de Enfermedades Sistémicas, Nuerología, Anatomía Patológica, Hospital Clínico San Cecilio, Granada. rriosfer@hotmail.com
Abstract:
Sarcoidosis is a multisystemic disease which diagnosis depends on the presence of nonnecrotizing granulomas in the biopsy. However there are variants such as necrotizing sarcoidal granulomas or nodular sarcoidosis which have atypical findings and make difficult the differential diagnosis with other infectious processes. We describe a case of a man who develops granulomas with extensive necrosis in a systemic sarcoidosis that affected the lung and the central nervous system. This finding made us to make the diagnosis of tuberculosis and delay the specific treatment.
Related Concept Videos
Cryptococcal Meningitis
Rabies
Encephalitis ll: Pathophysiology
Rocky Mountain Spotted Fever
Multiple Sclerosis l: Introduction
Diphtheria