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Updated: Jul 6, 2026
10:29
Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans
Published on: June 4, 2014
Profiling techniques in nutrition and health research
Martin Kussmann1, Serge Rezzi, Hannelore Daniel
1BioAnalytical Science Department, Nestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, 1000 Lausanne 26, Switzerland.
Current Opinion in Biotechnology
|April 2, 2008
Summary
Nutrition sciences use transcriptomics, proteomics, and metabolomics to understand how the body adapts to diet. Integrating these
Area of Science:
- Nutrition Sciences
- Molecular Biology
- Biochemistry
Background:
- Nutrition sciences increasingly utilize 'omics' technologies for molecular assessment of dietary adaptations.
- Transcriptomics offers a broad view of molecular changes due to dietary interventions.
- Proteomics and metabolomics provide deeper insights into biological responses.
Purpose of the Study:
- To highlight the roles of transcriptomics, proteomics, and metabolomics in nutrition science.
- To discuss the challenges and benefits of each 'omics' approach.
- To advocate for the integrated application of 'omics' in nutritional research.
Main Methods:
- Transcriptomics analysis for holistic molecular changes.
- Proteomics for identifying biomarkers and intervention targets, including bioactive food components.
- Metabolomics for individual metabolic characterization and health/disease endpoints.
Main Results:
- Transcriptomics provides a comprehensive overview of dietary impacts.
- Proteomics, despite its complexity, yields crucial intervention targets and identifies bioactive food elements.
- Metabolomics offers insights into individual metabolic states and their relation to health outcomes.
Conclusions:
- Integrated 'omics' approaches are essential in nutrition science.
- These integrated methods can elucidate biomarkers for personalized nutrition and assess food efficacy.
- Combining transcriptomics, proteomics, and metabolomics enhances understanding of diet-body interactions.
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