Related Experiment Video
Updated: Jul 6, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
Published on: November 30, 2015
Substance use, post-traumatic stress disorder and violence
1University of Missouri-St Louis, School of Social Work, St Louis, Missouri 63121, USA. Sharon_Johnson@umsl.edu
Substance use disorder and post-traumatic stress disorder frequently co-occur, particularly when violence is involved. Inconsistent measurement hinders understanding of this complex comorbidity.
Area of Science:
- Psychiatry
- Clinical Psychology
- Neuroscience
Background:
- Substance use disorder (SUD) and post-traumatic stress disorder (PTSD) are frequently comorbid conditions.
- Violence exposure is a significant risk factor for developing PTSD and can influence SUD development and severity.
Purpose of the Study:
- To review the co-occurrence of SUD and PTSD.
- To examine measurement issues in assessing this comorbidity.
- To highlight the role of violence in contributing to SUD and PTSD.
Main Methods:
- Systematic literature review.
- Analysis of studies examining SUD and PTSD.
- Focus on measurement consistency and violence as a factor.
Main Results:
- PTSD symptoms, with or without a formal diagnosis, are commonly comorbid with various substance use dependencies.
- The severity of substance use varies among individuals with comorbid PTSD.
- Inconsistent methodologies for classifying substance use and measuring PTSD symptoms across studies complicate comparisons.
Conclusions:
- Lack of standardized measurement and classification hinders accurate comparisons of SUD and PTSD comorbidity rates.
- Further research is needed to understand the role of violence in this comorbidity and its impact on treatment.
- Improved diagnostic consistency is crucial for advancing research and clinical practice in managing comorbid SUD and PTSD.
Related Concept Videos
Post-traumatic Stress Disorder
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Drug Abuse and Addiction: Pharmacological Phenomena
Dissociative Disorders
Dissociative Fugue
A hallmark feature of dissociative disorders is the dissociative fugue...
Introduction to Stress and Lifestyle
