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A systematic review on the Rosa canina effect and efficacy profiles
Cosima Chrubasik1, Basil D Roufogalis, Ulf Müller-Ladner
1Department of Forensic Medicine, University of Freiburg, Albertstr. 9, 79104 Freiburg, Germany.
Phytotherapy Research : PTR
|April 4, 2008
Summary
Rose hip (Rosa canina L.) preparations show antioxidative and anti-inflammatory effects. Further research is needed to confirm clinical significance for osteoarthritis and other conditions.
Area of Science:
- Pharmacology and Phytomedicine
- Traditional Medicine Re-evaluation
Background:
- German Commission E monographs negatively assessed rose hip preparations due to insufficient evidence.
- A comprehensive literature review was conducted to reevaluate Rosa canina L.'s traditional medicinal uses.
Purpose of the Study:
- To summarize the pharmacological and clinical effects of Rosa canina L.
- To reassess the evidence for rose hip's therapeutic utility.
Main Methods:
- Comprehensive literature review of pharmacological and clinical studies on Rosa canina L. preparations.
- Analysis of studies involving rose hip and rose hip seed powder (Litozin).
Main Results:
- Antioxidative and anti-inflammatory effects demonstrated for rose hip and rose hip seed preparations, attributed to lipophilic constituents.
- Exploratory studies show success with Litozin for osteoarthritis, rheumatoid arthritis, and low back pain.
- Potential benefits for weight management and ulcer prevention suggested by rose hip seed properties.
Conclusions:
- Rose hip exhibits promising antioxidative and anti-inflammatory properties, warranting further clinical investigation.
- Clinical significance of effects for various indications requires determination.
- Further research is necessary to clarify the clinical importance of experimental findings and optimize rose hip seed oil for topical use.
