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Related Concept Videos

Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

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Related Experiment Video

Updated: Jul 6, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Extranodal lymphoma.

Judith A Ferry1

  • 1Department of Pathology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA. jferry@partners.org

Archives of Pathology & Laboratory Medicine
|April 4, 2008
PubMed
Summary
This summary is machine-generated.

Extranodal lymphomas, cancers originating outside lymph nodes, present diverse types and features. This review explores common extranodal lymphomas, highlighting their unique characteristics and associations.

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Last Updated: Jul 6, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Lymphomas can originate in sites beyond the lymphatic system, termed extranodal lymphomas.
  • These extranodal lymphomas exhibit significant variability in type and presentation depending on the affected site.
  • Distinctive clinicopathologic features characterize many extranodal lymphomas.

Purpose of the Study:

  • To provide a comprehensive review of lymphomas commonly found in extranodal sites.
  • To elucidate the varied types and clinicopathologic features of extranodal lymphomas.
  • To discuss potential associations of extranodal lymphomas with other conditions.

Main Methods:

  • Literature review of extranodal lymphomas.
  • Analysis of clinicopathologic features.
  • Identification of common extranodal lymphoma types.

Main Results:

  • Extranodal lymphomas encompass a wide spectrum of lymphoid malignancies.
  • Specific extranodal sites are predisposed to particular lymphoma subtypes.
  • Associations with immunodeficiency, autoimmune diseases, infections, and ethnic predispositions are noted.

Conclusions:

  • Understanding the diversity of extranodal lymphomas is crucial for accurate diagnosis and management.
  • Extranodal lymphomas possess unique features that warrant specific consideration.
  • Further research into the etiology and associations of extranodal lymphomas is beneficial.