Related Experiment Video
Updated: Jul 6, 2026

Characterizing Mediated Extracellular Electron Transfer in Lactic Acid Bacteria with a Three-Electrode, Two-Chamber Bioelectrochemical System
Published on: August 23, 2024
Lactic acid production by Lactobacillus delbrueckii in a dual reactor system using packed bed biofilm reactor
V Rangaswamy1, S V Ramakrishna
1Industrial Biotechnology Group, Reliance Life Sciences Pvt. Ltd, Navi Mumbai, India. vidhya_rangaswamy@relbio.com
Aims:
An integrated dual reactor system for continuous production of lactic acid by Lactobacillus delbrueckii using biofilms developed on reticulated polyurethane foam (PUF) is demonstrated.
Methods And Results:
Lactobacillus delbrueckii was immobilized on PUF, packed in a bioreactor and used in lactic acid fermentation. The rate of lactic acid production was significantly high with a volumetric productivity of 5 g l(-1) h(-1) over extended period of time. When coupled to a bioreactor, the system could be operated as dual reactor for over 1000 h continuously without augmentation of inoculum and no compromise on productivity.
Conclusions:
Polyurethane foams offer an excellent support for biofilm formation.
Significance And Impact Of The Study:
The system was very robust and could be operated for prolonged period at a volumetric productivity of 4-6 g l(-1) h(-1).
Related Concept Videos
Production of Organic Acids
Bioreactor Design and Operational System
Bioreactor Controls-II
Microbes in the Production of Fermented Foods
Microbes in Food Production
Bioreactor Controls-I

