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Choroidal plasmacytoma in a patient with multiple myeloma. Diagnosis by fine-needle aspiration biopsy
Melis Palamar1, Carol L Shields, Fariba Ghassemi
1Ocular Oncology Service Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, USA.
Background:
To report a case of a secondary plasmacytoma of the choroid.
Methods:
Interventional case report with cytopathologic correlation.
Results:
A 61-year-old male with a breast nodule and a 2-year history of multiple myeloma developed blurred vision and was found to have three confluent, ill-defined areas of choroidal thickening in the left eye. Cytopathology and immunohistochemistry of a transocular fine-needle aspiration biopsy of the largest lesion revealed atypical plasma cells diagnostic of plasmacytoma. Following external beam radiotherapy the choroidal tumors resolved completely.
Conclusion:
Secondary plasmacytoma, despite its rarity, should be included in the differential diagnosis of amelanotic choroidal tumors, particularly in patients with multiple myeloma. Radiotherapy is an effective treatment.
