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Updated: Jul 6, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Psoriasiform dermatoses.

Virendra N Sehgal¹, Sunil Dogra, Govind Srivastava

¹Dermato-Venereology (Skin/VD) Centre, Sehgal Nursing Home, Panchwati, Azadpur, New Delhi, India. drsehgal@ndf.vsnl.net.in

Indian Journal of Dermatology, Venereology and Leprology

|April 5, 2008

Summary

Psoriasiform reaction pattern is a common skin response to various conditions, including infections, allergies, and malignancies. It requires careful observation to determine the exact underlying dermatological disorder.

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Last Updated: Jul 6, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

Dermatology
Pathology

Background:

Psoriasiform reaction pattern is a frequent finding in diverse dermatological conditions.
This pattern can be triggered by internal or external stimuli, including allergic, infective, parasitic, bacterial, fungal, viral, and malignant agents.

Purpose of the Study:

To highlight the diagnostic challenges posed by psoriasiform dermatoses.
To emphasize the need for thorough investigation to identify the precise underlying cause.

Main Methods:

Review of clinical and histopathological presentations of psoriasiform dermatoses.
Analysis of factors influencing the evolution and significance of the pattern.
Discussion of diagnostic confirmation methods, such as provocation tests.

Main Results:

The psoriasiform pattern's presentation and significance vary with the specific dermatosis and lesion age.
Clinico-histopathological disparity can complicate diagnosis, necessitating sustained observation.
Increased instances of psoriasiform drug eruptions and associations with HIV/AIDS and malignancies are noted.

Conclusions:

Psoriasiform dermatoses should be considered an initial descriptive term, not a definitive diagnosis.
Accurate diagnosis requires astute observation and investigation to unveil the exact underlying condition.
Recognition of psoriasiform eruptions is crucial for identifying associated systemic diseases, including malignancies and HIV/AIDS.